ENTRY EC 2.1.1.125
NAME Histone-Arginine N-methyltransferase
Histone protein methylase
Protein-Arginine N-methyltransferase
Protein methylase I
CLASS Transferases
Transferring one-carbon groups
Methyltransferases
REACTION S-Adenosyl-L-methionine + Histone L-arginine =
S-Adenosyl-L-homocysteine + Histone N-methyl-L-arginine
SUBSTRATE S-Adenosyl-L-methionine
Histone L-arginine
PRODUCT S-Adenosyl-L-homocysteine
Histone N-methyl-L-arginine
COMMENT Forms the N(G)-Monomethyl- and the N(G),N'(G)-Dimethyl-, but not
the N(G),N'(G)-Dimethyl-arginine derivatives.
DBLINKS University of Geneva ENZYME DATA BANK: 2.1.1.125
WIT (What Is There) Metabolic Reconstruction: 2.1.1.125
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