ENTRY       EC 2.1.1.122
NAME        (S)-Tetrahydroprotoberberine N-methyltransferase
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
REACTION    S-Adenosyl-L-methionine + (S)-7,8,13,14-Tetrahydroprotoberberine =
            S-Adenosyl-L-homocysteine + cis-N-Methyl-(S)-7,8,13,14-
            $tetrahydroprotoberberine
SUBSTRATE   S-Adenosyl-L-methionine
            (S)-7,8,13,14-Tetrahydroprotoberberine
PRODUCT     S-Adenosyl-L-homocysteine
            cis-N-Methyl-(S)-7,8,13,14-tetrahydroprotoberberine
COMMENT     Involved in the biosynthesis of Isoquinoline alkaloids in plants.
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.122
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.122
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