ENTRY       EC 2.1.1.118
NAME        Columbamine O-methyltransferase
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
REACTION    S-Adenosyl-L-methionine + Columbamine =
            S-Adenosyl-L-homocysteine + Palmatine
SUBSTRATE   S-Adenosyl-L-methionine
            Columbamine
PRODUCT     S-Adenosyl-L-homocysteine
            Palmatine
COMMENT     The product of this reaction is a protoberberine alkaloid that is
            widely distributed in the plant kingdom.
            Distinct in specificity from EC 2.1.1.88.
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.118
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.118
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