ENTRY       EC 2.1.1.116
NAME        3'-Hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltrandferase
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
REACTION    S-Adenosyl-L-methionine + 3'-Hydroxy-N-methyl-(S)-coclaurine =
            S-Adenosyl-L-homocysteine + (S)-Reticuline
SUBSTRATE   S-Adenosyl-L-methionine
            3'-Hydroxy-N-methyl-(S)-coclaurine
PRODUCT     S-Adenosyl-L-homocysteine
            (S)-Reticuline
COMMENT     Involved in Isoquinoline alkaloid metabolism in plants.
            Has also been shown to catalyse the methylation of (R,S)-
            Laudanosoline, (S)-3'-Hysroxycoclaurine and (R,S)-7-O-
            Methylnoraudanosine.
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.116
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.116
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