ENTRY       EC 2.1.1.113
NAME        Site-specific DNA-methyltransferase (cytosine-N4-specific)
            Modification methylase
            Restriction-modification system
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
SYSNAME     S-Adenosyl-L-methionine:DNA-cytosine N-methyltransferase
REACTION    S-Adenosyl-L-methionine + DNA cytosine =
            S-Adenosyl-L-homocysteine + DNA N4-methylcytosine
SUBSTRATE   S-Adenosyl-L-methionine
            DNA cytosine
PRODUCT     S-Adenosyl-L-homocysteine
            DNA N4-methylcytosine
COMMENT     This is a large group of enzymes, the majority of which, with
            enzymes of similar specificity listed as EC 3.1.21.3, 4 and 5,
            form so-called 'restriction-modification systems',  A complete
            listing of all these enzymes has been produced by R.J. Roberts
            (4143); this list is upated annually.
            4143. Roberts, R.J.(1990) Nucleic Acids Res. 18, 2331 [2.1.1.73,
            2.1.1.74, 2.1.1.113, 3.1.21.3, 3.1.21.4, 3.1.21.5].
MOTIF       PS: PS00092  [LIVAC]-[LIVFYWA]-x-[DN]-P-P-[FYW]
            PS: PS00093  [LIVMF]-T-S-P-P-[FY]
GENES       MJA: MJ0985 MJ1498
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.113
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.113
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