ENTRY       EC 2.1.1.107
NAME        Uroporphyrin-III C-methyltransferase
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
SYSNAME     S-Adenosyl-L-methionine:uroporphyrin-III C-methyltransferase
REACTION    S-Adenosyl-L-methionine + Uroporphyrin III =
            S-Adenosyl-L-homocysteine + Sirohydrochlorin
SUBSTRATE   S-Adenosyl-L-methionine
            Uroporphyrin III
PRODUCT     S-Adenosyl-L-homocysteine
            Sirohydrochlorin
COMMENT     Involved in the biosynthesis of siroheme and cobalamin.
PATHWAY     PATH: MAP00860  Porphyrin and chlorophyll metabolism
MOTIF       PS: PS00839  [LIVM]-[GS]-[STA]-G-P-G-x(3)-[LIVMFY]-[LIVM]-T-[LIVM]-
                         [KRHQG]-[AG]
            PS: PS00840  V-x(2)-[LI]-x(2)-G-D-x(3)-[FYW]-[GS]-x(8)-[LIF]-x(5,6)-
                         [LIVMFYWP]-x-[LIVM]-x-P-G
GENES       MJA: MJ0965
            ECO: b3803(hemX)
            HIN: HI0603(hemX)
            BSU: nasF(nasBE) ylnD
            SYN: hemX) sll0378(cysG) slr0106(ECOLI_3709
            SCE: YKR069W
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.107
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.107
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