ENTRY       EC 2.1.1.101
NAME        Macrocin O-methyltransferase
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
SYSNAME     S-Adenosyl-L-methionine:macrocin 3'''-O-methyltransferas
REACTION    S-Adenosyl-L-methionine + Macrocin = S-Adenosyl-L-homocysteine +
            Tylosin
SUBSTRATE   S-Adenosyl-L-methionine
            Macrocin
            Lactenosin
PRODUCT     S-Adenosyl-L-homocysteine
            Tylosin
            Desmycocin
COMMENT     The 3-hydroxy group of a 2-O-methyl-6-deoxy-D-allose reisidue in
            the macrolide antibiotic macrosin acts as methyl acceptor; also
            converts lactenosin into desmycocin.  Not identical with
            EC 2.1.1.102.
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.101
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.101
///