ENTRY       EC 2.1.1.100
NAME        Protein-S-isoprenylsysteine O-methyltransferase
            Isoprenylcysteine carboxylmethyltransferase
CLASS       Transferases
            Transferring one-carbon groups
            Methyltransferases
SYSNAME     S-Adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine
            $ O-methyltransferase
REACTION    S-Adenosyl-L-methionine +
            Protein C-terminal S-farnesyl-L-cysteine =
            S-Adenosyl-L-homocysteine +
            Protein C-terminal S-farnesyl-L-cysteine methyl ester
SUBSTRATE   S-Adenosyl-L-methionine
            Protein C-terminal S-farnesyl-L-cysteine
PRODUCT     S-Adenosyl-L-homocysteine
            Protein C-terminal S-farnesyl-L-cysteine methyl ester
COMMENT     C-terminal S-geranylgeranylcysteine and S-geranylcysteine residues
            are also methylated, more slowly.
GENES       SCE: YDR410C(STE14)
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.1.100
            WIT (What Is There) Metabolic Reconstruction: 2.1.1.100
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