ENTRY       EC 1.97.1.4
NAME        [Pyruvate Formate-lyase] activating enzyme
            PFL activase
CLASS       Oxidoreductases
            Other oxidoreductases
            Other oxidoreductases
REACTION    S-Adenosyl-L-methionine + Dihydroflavodoxin +
            [Pyruvate formate-lyase]-glycine = 5'-Deoxyadenosine + Methionine +
            Flavodoxin + [Pyruvate formate-lyase]-glycine radical
SUBSTRATE   S-Adenosyl-L-methionine
            Dihydroflavodoxin
            [Pyruvate formate-lyase]-glycine
PRODUCT     5'-Deoxyadenosine
            Methionine
            Flavodoxin
            [Pyruvate formate-lyase]-glycine radical
COMMENT     A single Glycine residue in Pyruvate Formate-lyase (EC 2.3.1.54) is
            oxidised to the corresponding radical Glycine, by transfer of H
            from its CH2 into adomet with concomitant cleavage of the latter.
MOTIF       PS: PS01087  G-x-G-x-R-x(3)-F-x(2)-G-C-x(3)-C-x(2)-C-x-N
GENES       MJA: MJ0808 MJ1227
            MTH: MTH1395 MTH1586 MTH1643 MTH1784 MTH345 MTH976
            ECO: b0902(pflA) b3952(pflC)
            HIN: HI0179(pflA)
DBLINKS     University of Geneva ENZYME DATA BANK: 1.97.1.4
            WIT (What Is There) Metabolic Reconstruction: 1.97.1.4
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