ENTRY       EC 1.7.99.4
NAME        Nitrate reductase
            Respiratory nitrate reductase
CLASS       Oxidoreductases
            Acting on other nitrogenous compounds as donors
            With other acceptors
SYSNAME     Nitrite:(acceptor) oxidoreductase
REACTION    Nitrite + Acceptor = Nitrate + Reduced acceptor;
            Nitrite + Ubiquinone = Nitrate + Ubiquinol
SUBSTRATE   Nitrite
            Acceptor
PRODUCT     Nitrate
            Reduced acceptor
            Benzyl viologen
COFACTOR    Cytochrome
            Molybdenum
            Iron
COMMENT     Contains molybdenum as a cofactor at active site.  Other subunits
            contain cytochrome c and iron-sulfur cluster.  Cytochrome c 
            subunit is transmembrane type,  Active subunit locates at 
            cytosol side.
PATHWAY     PATH: MAP00910  Nitrogen metabolism
MOTIF       PS: PS00490  [STA]-x-[STAC](2)-x(2)-[STA]-D-[LIVMY](2)-L-P-x-
                         [STAC](2)-x(2)-E
            PS: PS00551  [STAN]-x-[CH]-x(2,3)-C-[STAG]-[GSTVF]-x-C-x-[LIVMFYW]-
                         x-[LIVMA]-x(3,4)-[DNQKH]
            PS: PS00932  A-x(3)-[GDT]-I-x-[DNQTK]-x-[DEA]-x-[LIVM]-x-[LIVMC]-x-
                         [NS]-x(2)-[GS]-x(5)-A-x-[LIVM]-[ST]
GENES       MTH: MTH1567
            ECO: b1224(narG) b1225(narH) b1226(narJ) b1227(narI) b1465(narV)
                 b1466(narW) b1467(narY) b1468(narZ) b2206(napA)
            BSU: narG narH narI narJ nasC(narB)
            SYN: narJ) sll1454(narB) slr0479 slr0930(ECOLI_1188 ssl1552
DBLINKS     University of Geneva ENZYME DATA BANK: 1.7.99.4
            WIT (What Is There) Metabolic Reconstruction: 1.7.99.4
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