ENTRY       EC 1.4.3.13
NAME        Protein-lysine 6-oxidase
CLASS       Oxidoreductases
            Acting on the CH-NH2 group of donors
            With oxygen as acceptor
SYSNAME     Protein-L-lysine:oxygen 6-oxidoreductase (deaminating)
REACTION    Peptidyl-L-lysyl-peptide + H2O + O2 =
            Peptidyl-allysyl-peptide + NH3 + H2O2
SUBSTRATE   Peptidyl-L-lysyl-peptide
            H2O
            O2
            Protein 5-hydroxylysine
PRODUCT     Peptidyl-allysyl-peptide
            NH3
            H2O2
COMMENT     Also acts on protein 5-hydroxylysine.
DISEASE     MIM: 153455  Lysyl oxidase; Cutis laxa, recessive, type I, 219100
                         (1)
MOTIF       PS: PS00926  W-E-W-H-S-C-H-Q-H-Y-H
GENES       HSA: LOX(Hs.79234)
DBLINKS     University of Geneva ENZYME DATA BANK: 1.4.3.13
            WIT (What Is There) Metabolic Reconstruction: 1.4.3.13
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