ENTRY       EC 1.4.1.12
NAME        2,4-Diaminopentanoate dehydrogenase
CLASS       Oxidoreductases
            Acting on the CH-NH2 group of donors
            With NAD+ or NADP+ as acceptor
SYSNAME     2,4-Diaminopentanoate:NAD(P)+ oxidoreductase (deaminating)
REACTION    2,4-Diaminopentanoate + H2O + NAD+ or NADP+ =
            2-Amino-4-oxopentanoate + NH3 + NADH or NADPH
SUBSTRATE   2,4-Diaminopentanoate
            H2O
            NAD+
            NADP+
PRODUCT     2-Amino-4-oxopentanoate
            NH3
            NADH
            NADPH
COMMENT     Also acts, more slowly, on 2,5-diaminohexanoate forming 2-amino-
            -5-oxohexanoate, which then cyclizes non-enzymically to
            1-pyrroline-2-methyl-5-carboxylate.
PATHWAY     PATH: MAP00300  Lysine biosynthesis
            PATH: MAP00330  Arginine and proline metabolism
            PATH: MAP00472  D-Arginine and D-ornithine metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.4.1.12
            WIT (What Is There) Metabolic Reconstruction: 1.4.1.12
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