ENTRY EC 1.3.3.6
NAME Acyl-CoA oxidase
CLASS Oxidoreductases
Acting on the CH-CH group of donors
With oxygen as acceptor
SYSNAME Acyl-CoA:oxygen 2-oxidoreductase
REACTION Acyl-CoA + O2 = trans-2,3-Dehydroacyl-CoA + H2O2
SUBSTRATE Acyl-CoA
O2
PRODUCT trans-2,3-Dehydroacyl-CoA
H2O2
COFACTOR FAD
COMMENT A flavoprotein (FAD). Acts on CoA derivatives of fatty acids
with chain length from 8 to 18.
PATHWAY PATH: MAP00071 Fatty acid metabolism
DISEASE MIM: 264470 Acyl-Coenzyme A oxidase; Adrenoleukodystrophy,
pseudoneonatal (2)
MOTIF PS: PS00342 [SAGCN]-[RKH]-[LIVMAF]>
GENES SCE: YGL205W(FOX1)
HSA: ACOX
DBLINKS University of Geneva ENZYME DATA BANK: 1.3.3.6
WIT (What Is There) Metabolic Reconstruction: 1.3.3.6
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