ENTRY       EC 1.3.3.3
NAME        Coproporphyrinogen oxidase
            Coproporphyrinogenase
CLASS       Oxidoreductases
            Acting on the CH-CH group of donors
            With oxygen as acceptor
SYSNAME     Coproporphyrinogen:oxygen oxidoreductase(decarboxylating)
REACTION    Coproporphyrinogen-III + O2 = Protoporphyrinogen-IX + 2 CO2
SUBSTRATE   Coproporphyrinogen-III
            O2
PRODUCT     Protoporphyrinogen-IX
            CO2
PATHWAY     PATH: MAP00860  Porphyrin and chlorophyll metabolism
DISEASE     MIM: 121300  Coproporphyrinogen oxidase; Coproporphyria (3);
                         Harderoporphyrinuria (3)
MOTIF       PS: PS01021  K-x-W-C-D-x-[FYH](3)-[LIVM]-x-H-R-x-E-x-R-G-[LIVM]-G-G-
                         [LIVM]-F-F-D-D
GENES       ECO: b2436(hemF)
            SYN: sll1185(hemF)
            SCE: YDR044W(HEM13)
            HSA: CPO(CPX)
DBLINKS     University of Geneva ENZYME DATA BANK: 1.3.3.3
            WIT (What Is There) Metabolic Reconstruction: 1.3.3.3
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