ENTRY EC 1.14.15.5
NAME Corticosterone 18-monooxygenase
Corticosterone 18-hydroxylase
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With a reduced iron-sulfur protein as one donor, and
incorporation of one atom of oxygen
SYSNAME Corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase
$ (18-hydroxylating)
REACTION Corticosterone + Reduced adrenal ferredoxin + O2 =
18-Hydroxycorticosterone + Oxidized adrenal ferredoxin + H2O
SUBSTRATE Corticosterone
Reduced adrenal ferredoxin
O2
PRODUCT 18-Hydroxycorticosterone
Oxidized adrenal ferredoxin
H2O
PATHWAY PATH: MAP00140 C21-Steroid hormone metabolism
DBLINKS University of Geneva ENZYME DATA BANK: 1.14.15.5
WIT (What Is There) Metabolic Reconstruction: 1.14.15.5
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