ENTRY EC 1.14.13.35
NAME Anthranilate 3-monooxygenase (deaminating)
Anthranilate hydroxylase
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With NADH or NADPH as one donor, and incorporation of one atom of
oxygen
SYSNAME Anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating,
$ deaminating)
REACTION Anthranilate + NADPH + O2 = 2,3-Dihydroxybenzoate + NADP+ + NH3
SUBSTRATE Anthranilate
NADPH
O2
PRODUCT 2,3-Dihydroxybenzoate
NADP+
NH3
COMMENT The enzyme from Aspergillus niger is an iron protein; that from
the yeast Trichosporon cutaneum is a flavoprotein (FAD).
Previously EC 1.14.12.2.
PATHWAY PATH: MAP00360 Phenylalanine metabolism
PATH: MAP00910 Nitrogen metabolism
DBLINKS University of Geneva ENZYME DATA BANK: 1.14.13.35
WIT (What Is There) Metabolic Reconstruction: 1.14.13.35
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