ENTRY       EC 1.14.12.3
NAME        Benzene 1,2-dioxygenase
            Benzene hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of two atoms
            of oxygen into one donor
SYSNAME     Benzene,NADH:oxygene 1,2-oxidoreductase
REACTION    Benzene + NADH + O2 = cis-1,2-Dihydrobenzene-1,2-diol + NAD+
SUBSTRATE   Benzene
            NADPH
            O2
PRODUCT     cis-1,2-Dihydrobenzene-1,2-diol
            NAD+
COFACTOR    Iron
            Sulfur
            FAD
COMMENT     A system, containing a reductase which is an iron-sulfur
            flavoprotein (FAD), an iron-sulfur oxygenase and ferredoxin.
            Requires Fe2+.
MOTIF       PS: PS00570  C-x-H-R-G-x(8)-G-N-x(5)-C-x-[FY]-H
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.12.3
            WIT (What Is There) Metabolic Reconstruction: 1.14.12.3
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