ENTRY       EC 1.14.12.10
NAME        Benzoate 1,2-dioxygenase
            Benzoate hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With NADH or NADPH as one donor, and incorporation of two atoms
            of oxygen into one donor
SYSNAME     Benzoate,NADH:oxygen oxidoreductase
            (1,2-hydroxylating, decarboxylating)
REACTION    Benzoate + NADH + O2 = Catechol + CO2 + NAD+
SUBSTRATE   Benzoate
            NADH
            O2
PRODUCT     Catechol
            CO2
            NAD+
COFACTOR    Iron
            Sulfur
            FAD
COMMENT     A system, containing a reductase which is an iron-sulfur
            flavoprotein (FAD), and an iron-sulfur oxygenase. Requires Fe2+.
PATHWAY     PATH: MAP00360  Phenylalanine metabolism
MOTIF       PS: PS00570  C-x-H-R-G-x(8)-G-N-x(5)-C-x-[FY]-H
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.12.10
            WIT (What Is There) Metabolic Reconstruction: 1.14.12.10
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