ENTRY EC 1.14.11.9
NAME Naringenin 3-dioxygenase
Flavanone 3-hydroxylase
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With 2-oxoglutarate as one donor, and incorporation of one atom
each of oxygen into both donors
SYSNAME Naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
REACTION Naringenin + 2-Oxoglutarate + O2 = Dihydrokaempferol +
Succinate + CO2
SUBSTRATE Naringenin
2-Oxoglutarate
O2
PRODUCT Dihydrokaempferol
Succinate
CO2
COFACTOR Iron
Ascorbate
COMMENT Requires Fe2+ and ascorbate.
PATHWAY PATH: MAP00940 Biosynthesis of flavonoids
DBLINKS University of Geneva ENZYME DATA BANK: 1.14.11.9
WIT (What Is There) Metabolic Reconstruction: 1.14.11.9
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