ENTRY       EC 1.14.11.8
NAME        Trimethyllysine dioxygenase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With 2-oxoglutarate as one donor, and incorporation of one atom
            each of oxygen into both donors
SYSNAME     N6,N6,N6-Trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase
            $ (3-hydroxylating)
REACTION    N6,N6,N6-Trimethyl-L-lysine + 2-Oxoglutarate + O2 =
            3-Hydroxy-N6,N6,N6-trimethyl-L-lysine + Succinate + CO2
SUBSTRATE   N6,N6,N6-Trimethyl-L-lysine
            2-Oxoglutarate
            O2
PRODUCT     3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
            Succinate
            CO2
COFACTOR    Iron
            Ascorbate
COMMENT     Requires Fe2+ and ascorbate.
PATHWAY     PATH: MAP00310  Lysine degradation
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.11.8
            WIT (What Is There) Metabolic Reconstruction: 1.14.11.8
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