ENTRY       EC 1.14.11.3
NAME        Pyrimidine-deoxynucleoside 2'-dioxygenase
            Thymidine 2'-hydroxylase
            Thymidine 2-oxoglutarate dioxygenase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With 2-oxoglutarate as one donor, and incorporation of one atom
            each of oxygen into both donors
SYSNAME     2-Deoxyuridine,2-oxoglutarate:oxygen oxidoreductase
            $ (2'-hydroxylating)
REACTION    2-Deoxyuridine + 2-Oxoglutarate + O2 = Uridine + Succinate + CO2
SUBSTRATE   2-Deoxyuridine
            2-Oxoglutarate
            O2
            Thymidine
PRODUCT     Uridine
            Succinate
            CO2
COFACTOR    Iron
            Ascorbate
COMMENT     Requires Fe2+ and ascorbate. Also acts on thymidine. cf.
            EC 1.14.11.10.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.11.3
            WIT (What Is There) Metabolic Reconstruction: 1.14.11.3
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