ENTRY       EC 1.14.11.14
NAME        6beta-Hydroxyhyoscyamine epoxidase
            Hydroxyhyoscyamine dioxygenase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With 2-oxoglutarate as one donor, and incorporation of one atom
            each of oxygen into both donors
SYSNAME     (6S)-6-Hydroxyhyoscyamine,2-oxoglutarate oxidoreductase
            $ (epoxide-forming)
REACTION    (6S)-6-Hydroxyhyoscyamine + 2-Oxoglutarate + O2 = Scopolamine +
            Succinate + CO2
SUBSTRATE   (6S)-6-Hydroxyhyoscyamine
            2-Oxoglutarate
            O2
PRODUCT     Scopolamine
            Succinate
            CO2
COFACTOR    Iron
            Ascorbate
COMMENT     Requires Fe2+ and ascorbate.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.11.14
            WIT (What Is There) Metabolic Reconstruction: 1.14.11.14
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