ENTRY       EC 1.14.11.11
NAME        Hyoscyamine (6S)-dioxygenase
            Hyoscyamine 6beta-hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With 2-oxoglutarate as one donor, and incorporation of one atom
            each of oxygen into both donors
SYSNAME     L-Hyoscyamine,2-oxoglytarate:oxygen oxidoreductase
            ((6S)-hydroxylating)
REACTION    L-Hyoscyamine + 2-Oxoglutarate + O2 = (6S)-Hydroxyhyoscyamine +
            Succinate + CO2
SUBSTRATE   L-Hyoscyamine
            2-Oxoglutarate
            O2
PRODUCT     (6S)-Hydroxyhyoscyamine
            Succinate
            CO2
COFACTOR    Iron
            Ascorbate
COMMENT     Requires Fe2+ and ascorbate.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.11.11
            WIT (What Is There) Metabolic Reconstruction: 1.14.11.11
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