ENTRY EC 1.14.11.10
NAME Pyrimidine-deoxynucleoside 1'-dioxygenase
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With 2-oxoglutarate as one donor, and incorporation of one atom
each of oxygen into both donors
SYSNAME 2-Deoxyuridine,2-Oxoglutarate:oxygen oxidoreductase
$ (1'-hydroxylating)
REACTION 2-Deoxyuridine + 2-Oxoglutarate + O2 = Uracil +
Deoxyribonolactone + Succinate + CO2
SUBSTRATE 2-Deoxyuridine
2-Oxoglutarate
O2
PRODUCT Uracil
Deoxyribonolactone
Succinate
CO2
COFACTOR Iron
Ascorbate
COMMENT Requires Fe2+ and ascorbate. cf. EC 1.14.11.3.
DBLINKS University of Geneva ENZYME DATA BANK: 1.14.11.10
WIT (What Is There) Metabolic Reconstruction: 1.14.11.10
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