ENTRY       EC 1.13.12.5
NAME        Renilla-luciferin 2-monooxygenase
            Renilla-type luciferase
            Aequorin
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            (oxygenases)
            With incorporation of one atom of oxygen (internal monooxygenases
            or internal mixed function oxidases)
SYSNAME     Renilla-luciferin:oxygen 2-oxidoreductase (decarboxylating)
REACTION    Renilla luciferin + O2 = Oxidized Renilla luciferin + CO2 + hv
SUBSTRATE   Renilla luciferin
            O2
            8-Benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo-
            $[1,2a]pyrazin-3(7H)-one
PRODUCT     Oxidized Renilla luciferin
            CO2
            hv
COMMENT     8-Benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo-
            [1,2a]pyrazin-3(7H)-one is similar to, and as active as, luciferin
            from the coelenterate Renilla. The native luciferin has the benzyl
            group replaced by an unidentified group of approximately
            200 Da. Luciferases of other coelenterates also react with
            Renilla luciferin. The enzyme may be assayed by measurement
            of light emission.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.13.12.5
            WIT (What Is There) Metabolic Reconstruction: 1.13.12.5
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