ENTRY       EC 1.13.11.4
NAME        Gentisate 1,2-dioxygenase
            Gentisate oxygenase
CLASS       Oxidoreductases
            Acting on single donors with incorporation of molecular oxygen
            (oxygenases)
            With incorporation of two atoms of oxygen
SYSNAME     Gentisate:oxygen 1,2-oxidoreductase (decyclizing)
REACTION    2,5-Dihydroxybenzoate + O2 = Maleylpyruvate
SUBSTRATE   2,5-Dihydroxybenzoate
            O2
PRODUCT     Maleylpyruvate
COFACTOR    Iron
COMMENT     Requires Fe2+. Formerly EC 1.13.1.4 and 1.99.2.4.
PATHWAY     PATH: MAP00350  Tyrosine metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.13.11.4
            WIT (What Is There) Metabolic Reconstruction: 1.13.11.4
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