ENTRY       EC 1.13.11.37
NAME        Hydroxyquinol 1,2-dioxygenase
CLASS       Oxidoreductases
            Acting on single donors with incorporation of molecular oxygen
            (oxygenases)
            With incorporation of two atoms of oxygen
SYSNAME     Benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing)
REACTION    Benzene-1,2,4-triol + O2 = 3-Hydroxy-cis,cis-muconate
SUBSTRATE   Benzene-1,2,4-triol
            O2
PRODUCT     3-Hydroxy-cis,cis-muconate
COFACTOR    Iron
COMMENT     An iron protein. The product isomerizes to 2-maleylacetate
            (cis-hexenedioate). Highly specific; catechol and pyrogallol are
            acted on at less than 11436424f the rate at which hydroxyquinol is
            oxidized.
PATHWAY     PATH: MAP00360  Phenylalanine metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.13.11.37
            WIT (What Is There) Metabolic Reconstruction: 1.13.11.37
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