ENTRY       EC 1.13.11.25
NAME        3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione
            $ 4,5-dioxygenase
            Steroid 4,5-dioxygenase
            3-Alkylcatechol 2,3-dioxygenase
CLASS       Oxidoreductases
            Acting on single donors with incorporation of molecular oxygen
            (oxygenases)
            With incorporation of two atoms of oxygen
SYSNAME     3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:
            $oxygen 4,5-oxidoreductase (decyclizing)
REACTION    3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione +
            O2 = 3-Hydroxy-1,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-
            $dien-4-oate
SUBSTRATE   3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione
            O2
            3-Isopropylcatechol
            3-tert-Butyl-5-methylcatechol
PRODUCT     3-Hydroxy-1,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-
            $dien-4-oate
COFACTOR    Iron
COMMENT     Requires Fe2+. Also acts on 3-isopropylcatechol and
            3-tert-butyl-5-methylcatechol.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.13.11.25
            WIT (What Is There) Metabolic Reconstruction: 1.13.11.25
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