ENTRY       EC 1.13.11.12
NAME        Lipoxygenase
            Lipoxidase
            Carotene oxidase
CLASS       Oxidoreductases
            Acting on single donors with incorporation of molecular oxygen
            (oxygenases)
            With incorporation of two atoms of oxygen
SYSNAME     Linoleate:oxygen oxidoreductase
REACTION    Linoleate + O2 =
            (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoate
SUBSTRATE   Linoleate
            O2
PRODUCT     (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoate
COFACTOR    Iron
            PQQ
COMMENT     An iron protein. Also oxidizes other methylene-interrupted poly-
            unsaturated fatty acids. Formerly EC 1.13.1.13 & 1.99.2.1
            PQQ enzyme
MOTIF       PS: PS00081  [LIVMA]-H-P-[LIVM]-x-[KRQ]-[LIVMF](2)-x-[AP]-H
            PS: PS00711  H-[EQ]-x(3)-H-x-[LM]-[NQR]-[GST]-H-[LIVMSTAC](3)-E
STRUCTURES  PDB: 2SBL  
DBLINKS     University of Geneva ENZYME DATA BANK: 1.13.11.12
            WIT (What Is There) Metabolic Reconstruction: 1.13.11.12
            SCOP (Structural Classificaion of Proteins): 1.13.11.12
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