ENTRY       EC 1.13.11.10
NAME        7,8-Dihydroxykynurenate 8,8a-dioxygenase
            7,8-Dihydroxykynurenate oxygenase
CLASS       Oxidoreductases
            Acting on single donors with incorporation of molecular oxygen
            (oxygenases)
            With incorporation of two atoms of oxygen
SYSNAME     7,8-Dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing)
REACTION    7,8-Dihydroxykynurenate + O2 =
            5-(3-Carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylate
SUBSTRATE   7,8-Dihydroxykynurenate
            O2
PRODUCT     5-(3-Carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylate
COFACTOR    Iron
COMMENT     Requires Fe2+.  Formerly EC 1.13.1.10.
PATHWAY     PATH: MAP00380  Tryptophan metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.13.11.10
            WIT (What Is There) Metabolic Reconstruction: 1.13.11.10
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