ENTRY       EC 1.1.3.15
NAME        (S)-2-Hydroxy-acid oxidase
            Glycolate oxidase
            Hydroxy-acid oxidase A
            Hydroxy-acid oxidase B
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With oxygen as acceptor
SYSNAME     (S)-2-Hydroxy-acid:oxygen 2-oxidoreductase
REACTION    (S)-2-Hydroxy acid + O2 = 2-Oxo acid + H2O2
SUBSTRATE   (S)-2-Hydroxy acid
            O2
            Aliphatic hydroxy acid
            Aromatic hydroxy acid
PRODUCT     2-Oxo acid
            H2O2
COFACTOR    FMN
COMMENT     A flavoprotein (FMN). Exists as two major ioenzymes; the A form
            preferentially oxidizes short-chain aliphatic hydroxy acids, and
            was previously listed as EC 1.1.3.1, glycolate oxidase; the B
            form preferentially oxidizes long-chain and aromatic hydroxy
            acids. The rat isoenzyme B also acts as L-amino-acid oxidase
            (EC 1.4.3.2).
PATHWAY     PATH: MAP00630  Glyoxylate and dicarboxylate metabolism
MOTIF       PS: PS00342  [SAGCN]-[RKH]-[LIVMAF]>
            PS: PS00557  S-N-H-G-[AG]-R-Q
STRUCTURES  PDB: 1GYL  
DBLINKS     University of Geneva ENZYME DATA BANK: 1.1.3.15
            WIT (What Is There) Metabolic Reconstruction: 1.1.3.15
            SCOP (Structural Classificaion of Proteins): 1.1.3.15
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