ibclogo XVI International Botanical Congess


Abstract Number: 6101
Session = 8.14.1


TRANSGENE MANAGEMENT FOR THE POST GENOMICs ERA


Yuri Gleba, Icon Genetics, Inc.,Princeton, NJ 08542, USA


The market for genetically modified agricultural products is projected to reach anywhere from $100 to $500 billion in revenues in 2010-2015, an enormous increase over current startup levels ($0.5 billion). Genomics is considered to be the key technology to develop 2nd and 3rd generation products. Total genomics effort of just a few major companies such as DuPont, Novartis and Monsanto is well in excess of $1B, and will result in a myriad of new and useful genes within next few years.The cost of tools and the enabling technologies required to bring and manage these genes in crops is expected to increase proportionally to the sequencing rate and the research effort put into functional genomics. Our estimate of major bottlenecks of the gene discovery and crop engineering process make us believe that, besides an extensive set of genomics tools, a set of significantly more efficient transgene management technologies will be the primary need for major Life Sciences companies in the immediate future. The purpose of the lecture is to discuss the limitations of existing crop engineering tools, as well as to describe some promising emerging technologies, such as novel transformation and line conversion methods based on integrative transgene locus or artificial plant chromosome, gene regulation enabled through chemical gene switches, hybrid seed production methods, etc.


HTML-Version made 7. July 1999 by Kurt Stüber