XVI International Botanical Congess

Nodulisporic acid (NA), a new indole terpene, was isolated from an endophytic Nodulisporium sp. Twelve other Nodulisporiums also yielded NA. These strains came from 7 tropical countries. Cultural and microscopic features show that the NA-producing Nodulisporium strains are similar. Sequencing of the two internal transcribed spacers (ITS) and the 5.8S gene revealed that the isolates form into three groups using ITS1. The 2 groups with the longest sequences were the same. The isolates with shorter sequences had lower homology with the other groups in the ITS1, but those strains could not be distinguished from the other groups, according to ITS2. These data show that all the isolates belong to the same species, but divided into populations showing some degree of genetic variation.