XVII. D. Some Major Steps in the Development of Tetrapyrrole-Dependent Photobiotechnologies

1. 1961: Lipson et al, synthesized hematoporphyrin derivative (HPD), the first practical photodynamic therapy drug used in the treatment of cancer.
2. 1984: Rebeiz et al, described the concept and phenomenology of tetrapyrrole-dependent photodynamic herbicides.
3. 1986: Pottier et al, used delta-aminolevulinic acid (ALA)-induced protoprphyrin in the treatment of cancerous tumors.
4. 1988: Rebeiz et al, described the concept and phenomenology of tetrapyrrole-dependent photodynamic insecticides.
5. 1989: Matringe et al, demonstrated the inhibition of protoporphyrinogen IX oxidase by diphenyl ether herbicides.

References

1. Lipson, R. L., Baldes, E. J., Olsen A. M. (1961). J. Natl. Cancer. Inst. 26: 1-11.
2. Rebeiz, C. A., Montazer-Zouhoor, A., Hopen, H. J. and Wu, S. M. (1984). Photodynamic herbicides: Concept and phenomenology. Enzyme and Microbial Technology 6: 390-401.
3. Pottier, R. H., Chow, Y. F. A., LaPlante, J. P., Truscott, T. G., Kennedy, J. C., and Beiner, L. A. (1986). Photochem. Photobiol. 44: 679-687.
4. Rebeiz, C. A., Juvik, J. A., and Rebeiz, C. C. (1988). Porphyric insecticides. 1. Concept and phenomenology. Pesticide Biochem. and Physiol. 30: 11-27.
5. Matringe, M., Camadro, J. M., Labbe, P., Scalla, R. (989). Protoporphyrinogen oxidase as a molecular target for diphenyl ether herbicides. Biochem. J. 260: 231-235.